Wednesday 26 September 2012

EMQ practice - Treatment of respiratory infections

  • Standard therapy for community-acquired pneumococcal pnemonia not requiring hospital admission
    • Oral amoxicillin
      • Oral erythromycin if patient is allergic to penicillin
      • Can even combine with amoxicillin if an atypical organism is suspected
  • 35 year old, ward, pneumonia, HAI
    • Intravenous ceftazidime
      • Third generation cephalosporin for gram negative bacteria that causes HAI
  • 40 year old, builder, severe community acquired pneumonia, atypical pathogens
    • Intravenous cefuroxime and erythromycin
      • Standard therapy for community-acquired pneumonia
      • Rifampicin added empirically if high clinical suspicion of legionella infection
  • 22 year old, HIV positive, anti-retroviral therapy, Pneumocystic carinii pneumonia
    • Intravenous co-trimoxazole
      • Treatment of choice is high-dose co-trimoxazole delivered intravenously for 2-3 weeks
      • Intravenous pentamidine may be used if co-trimoxazole is contraindicated or not tolerated
      • Corticosteroids are used as an adjunct if there is hypoxaemia
      • Trimethoprim and sulfamethoxazole, folic acid synthesis inhibitors
  • 19 year old, male, pneumonia with symptoms of headache, fever and dry cough, chlamydia infection
    • Oral tetracycline
      • Chlamydial pneumonia often presents with a biphasic illness: upper respiratory tract symptoms precede pneumonia
      • Diagnosis is usually made retrospectively

1 comment:

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