Tuesday 25 September 2012

Carbon Monoxide Poisoning


  • Carbon monoxide combines readily with haemoglobin and prevents the formation of oxyhaemoglobin

Aetiology
  • Gas appliances with poor ventilation

Clinical features
  • Mental impairment
  • Nausea and vomiting
  • Headache
  • Hallucinations
  • Fit
  • Drowsiness and coma
  • Mild-moderate toxicity
    • Tachycardia
    • Tachypnoea
  • Severe toxicity
    • Hypotension
    • Bradycardia
    • Myocardial damage
    • Respiratory distress

Investigation
  • Blood carboxyhaemoglobin level

Management
  • Remove the sources
  • High-flow oxygen
  • Hyperbaric oxygen if
    • Coma
    • Carboxyhaemoglobin level >10%

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