Sunday 23 September 2012

EMQ practice: Emergency management: respiratory distress

Respiratory distress
  • 65 year old male, long standing COPD, severe shortness of breath, Oxygen and nebulised bronchodilators, Hour later: PaO2 6.0 kPa (on max. O2), PaCO2 16.0 kPa, pH 7.2
    • Nasal intermittent positive pressure ventilation
      • Exacerbation of COPD and Type II respiratory failure
      • Responded poorly to medical therapy
      • Non-invasive intermittent positive pressure ventilation (NIPPV)
      • Reduce need for formal intubation
      • Anaesthesia and intubation can be difficult in a patient with respiratory failure
      • NIPPV should be tried unless patient is in extremis
      • It does need the patient to be conscious and cooperative though
  • 17 year old woman, wheeze and marked perioral swelling, Now: PaO2 7.0 kPa (on 28% O2), PaCO2 4.1 kPa
    • 100% O2, intramuscular adrenaline, nebulised salbutamol
      • Acute anaphylaxis
      • Type I IgE-mediated hypersensitivity reaction
      • Rash, oedema, tachycardia, hypotension, and wheeze
      • Laryngeal oedema giving rise to upper airway obstruction in particularly worrying because it may impede endotracheal intubation
      • Initial treatment of choice:
        • 0.5ml epinephrine 1:1000 solution (500 micrograms) delivered intramuscularly which can be repeated in the absence of clinical improvement or if deterioration occurs
        • Intravenous epinepherine is dangerous and should only be given in dilution of 1:10000 in an immediately life-threatening situation (e.g. frank cardiac arrest)
  • 14 year old asthma, acute severe asthma attack, PaO2 10.0 kPa (on 28% O2), PaCO2 8.0kPa
    • 100% O2, nebulised salbutamol, intravenous hydrocortisone
      • Severe asthma attack features
        • Peak expiratory flow rate PEFR < 50%
        • Respiratory rate more than or = 25 breaths/min
        • Pulse more than or equals to 110 beats/min
        • Inability to complete sentence in 1 breath
      • Life-threatening asthma attack
        • PEFR <33%
        • Silent chest
        • Cyanosis
        • Poor respiratory effort
        • Bradycardia
        • Arrhythmia
        • Hypotension
        • Exhaustion
        • Confusion
        • PaO2 <8kPa
        • Acidosis with pH<7.35
        • High PaCO2
      • Intubation and transfer to ICU if patient does not respond to drug therapy
      • 100% O2 should be given since there is no risk of respiratory depression resulting from a hypoxic ventilatory drive
      • Between attacks CO2 should be within normal range
      • Common mistake to restrict oxygen to patients with asthma dn a high CO2
  • 28 year old male, RTA, severe respiratory distress, Examination reveals decreased expansion on right side of chest with mediastinal shift to the left
    • Right-sided decompression
      • Tension pneumothorax is a medical emergency
      • Cannula inserted into second intercostal space in the mid-clavicular line in the affected side until a functioning intercostal tube can be positioned
  • Young man, acute onset shortness of breath, decreased expansion on the right, SaO2 95%
    • Chest radiograph
      • Indicated here to confirm diagnosis of pneumothorax and assess the degree of collapse
      • In healthy patients a small penumothorax will often heal without further intervention
      • Patient should be observed for 6 hours and, if there is no increase in the size of the pneumothorax, may be discharged with early follow-up and repeated chest radiograph
      • Spontaneous pneumothoraces are relatively common in young adults (especially tall thin men) and older patients with emphysema
      • In patients with thoracic disease/large pneumothoraces, simple aspiration is recommended
      • If not working, then chest drain is required

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