Sunday 16 September 2012

EMQ practice - Causes of pneumonia

Causes of pneumonia:

  • 80 year old male, bilateral cavitating bronchopneumonia after an influenza infection
    • Staphylococcus aureus
      • Not common pathogen in community acquired pneumonia
      • May cause secondary infection in elderly recovering from influenza
      • IV drug users
      • Flucloxacillin is the treatment of choice for staphylococcal infection
  • 24 year old student, severe headache, fever, dry cough and arthralgia. Recently bought several parrots and was previously fit and well
    • Chlamydia psittaci
      • Rare cause of community acquired pneumonia
      • Lower respiratory tract symptoms and signs with exposure to birds
      • No acute diagnostic tests are available and diagnosis is made in retrospect by demonstrating a rising titre of complement-fixing antibody (same as other atypical cases like Legionella pneumophila
      • Macrolide antibiotic
  • 40 year old male, HIV, fever, dry cough, weight loss, exertional dyspnoea
    • Pneumocystis carinii
      • Common complication of HIV infection (AIDS-defining illness)
      • Opportunistic infection in other immunocompromised patients such as  those receiving immunosuppressive drugs and cancer chemotherapy
  • 75 year old male, headache, dry cough, anaemia, skin rash, blood tests detect cold agglutinins
    • Mycoplasma pneumoniae
      • Most common atypical cause of community-acquired pneumonia
      • Cases usually occur during an epidemic, which may give a clue to diagnosis
      • Characteristic feature of is the autoimmune haemolytic anaemia caused by the presence of cold agglutinins
      • Erythema multiforme, myopericarditis, and meningoencephalitis
      • Diagnosis often made in retrospect via detection of a rising antibody titre
      • Macrolide should be commenced if suspected
  • 25 year old air conditioning technician, flu-like symptoms, dry cough, radiograph shows multilobar shadowing, blood tests show hyponatraemia and lymphopenia, urinalysis reveals haematuria
    • Legionella pneumophila
      • Rare cause of atypical community pneumonia
      • Hyponatraemia and lymphopenia may assist in diagnosis
      • This can be performed rapidly by testing for the presence of legionella antigen in the urine (high sensitivity and specificity)
      • Adequate chlorination of water supply

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