Monday 15 October 2012

Pulmonary embolism

Obstruction of a branch of the pulmonary artery by clot from a DVT


Clinical features
  • Small or medium PE
    • Pleuritic chest pain
    • Shortness of breath
    • Haemoptysis in 30%
    • Tachypnoea
    • Pleural rub
    • Coarse crackles
    • Pleural effusion
  • Massive PE
    • Collapse
    • Shock
    • Cardiac arrest electromechanical dissociation
    • Elevated JVP ('a' wave)
    • Gallop rhythm
  • Recurrent PE
    • Breathlessness
    • Weakness
    • Syncope
    • Gradual deterioration

Investigation
  • Chest X-ray - oligaemic area
  • ECG
    • S wave in lead I, Q wave and invested T in lead III
    • Right axis deviation
    • Right bundle branch block
  • Fibrin degredation products (FDPs) and D-dimer in blood are elevated
  • V/Q scan
    • Radionucleotide scan
    • Demonstrates defects in perfusion of the lung in areas with normal ventilation
  • Blood gases - hypoxia and low PaCO2
  • Echcardiogram - high PA pressure
  • Pulmonary angiography / CT pulmonary angiogram

Management
  • High-flow oxygen
  • Analgesia
  • Intravenous heparin or
  • Low molecular weight heparin
  • Consider thrombolysis (rtPa)

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