Wednesday 17 October 2012

Fulminant hepatic failure

Aetiology
  • Hepatitis A/D/E
  • Drugs
    • Paracetamol
    • Volatile liquid anaesthetics
    • Isoniazid
    • Ecstasy
  • Wilson's disease
  • Pregnancy
  • Reye's syndrome

Clinical features
  • Jaundice
  • Encephalopathy
  • Drowsiness -> coma
  • Hypoglycaemia
  • Low potassium or calcium
  • Haemorrhage

Management
  • Treat on a specialist unit
  • Supportive therapy
  • Liver therapy

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