- Haematuria
- Proteinuria
- Hypertension
- Oedema
- Oliguria
- Uraemia
Aetiology
- Streptococcal throat infection or otitis media
- Systemic vasculitis
- Cryoglobulinaemia
Investigations
- General
- Urine microscopy for red cells and casts
- Serum urea and creatinine (raised)
- Creatinine clearance (low)
- 24 hour urine protein (raised)
- C3 and C4 (low)
- Chest X-ray for pulmonary oedema
- Renal imaging (usually normal)
- Diagnostic
- Throat swab
- Antistreptolysin O titre
- ANCA
- Anti-GBM antibody
- Cryoglobulins
Management
- Daily weight checks
- Fluid balance chart
- Antihypertensive
- BP monitoring
- Salt restriction
- Fluid restriction
- Diuretics
- Dialysis if needed
- Antibiotics for post-streptococcal infections
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