Tuesday 23 October 2012

Proton pump inhibitors

Omeprazole
Lansoprazole

Indications

  • Peptic ulcer healing
  • Reflux oesophagitis
  • H.pylori eradication

Mechanism of action
  • Reduce gastric acid secretion by blocking proton pumps

Side-effects
  • Diarrhoea 
  • Headache
  • Rash
  • Nausea

Cautions/contraindications
  • Liver disease

Interactions
  • Omeprazole - Warfarin

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