Gastric Adenocarcinoma

Epigastric pain is non-specific symptoms of upper-gastrointestinal pathology, but weight loss and anorexia are more sinister, with anaemia implying chronic gastrointestinal bleeding. The endoscopic appearance of a thickened rigid gastric wall suggests 'linitis plastica' (leather bottle stomach), a term used for gastric adenocarcinoma that diffusely infiltrates all layers of the gastric wall. The findings of numerous signet ring cells on biopsy confirms poorly differentiated (or diffuse) adenocarcinoma.