Mesial temporal sclerosis (hippocampal sclerosis) is a specific pattern of hippocampal neuron cell loss, and is divided into three categories based on 'sectors' affected.
- CA1 and CA4
- CA4 alone
- CA1 to CA4
- Hippocampal atrophy and gliosis
- Increased T2 signal
- May occur with other temporal lobe pathologies
- Most common feature in temporal lobe epilepsy
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