Thursday 15 November 2012

Antiviral therapies

Herpes Zoster Infection
  • Oral aciclovir


Cytomegalovirus (CMV)
  • 'Mozarrella and tomato pizza' appearance
  • Risk of blindness, HIV patients, medical emergency
  • Intravenous Ganciclovir
  • Foscarnet is also used 

Severe Respiratory Syncytial Virus (RSV) bronchiolitis
  • Inhaled ribavirin
  • Monoclonal antibody is now available that can be used to prevent RSV infection in infants at high risk (palivizumab)

Chronic hepatitis-C infection
  • Interferon-alpha given by subcutaneous injection
  • Combination therapy with ribavirin is more effective and should be continued for 6 months

HIV
  • TWO NUCLEOSIDE ANALOGUE REVERSE TRANSCRIPTASE INHIBITORS (AZT and didanosine)
  • ONE PROTEASE INHIBITOR (Indinavir)
  • Zidovudine + Didanosine
  • Indinavir

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