- Too much water loss in comparison to sodium loss (or no sodium change at all)
- Nephrogenic/pituitary diabetes insipidus
- Nausea, vomiting, fever, confusion
- Replace over 48 hours
Hyponatraemia
- Too little water loss in comparison to sodium loss (or no sodium change at all)
- SIADH
- Cerebral oedema causes headache, confusion, convulsions, coma
- Restrict water
- Vasopressin antagonists in the future?
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