Friday 4 January 2013

Chickenpox

Chickenpox is caused by primary infection with varicella zoster virus. Shingles is reactivation of dormant virus in dorsal root ganglion.

Chickenpox is highly infectious
  • Spread via the respiratory route
  • Can be caught from someone with Shingles
  • Infectivity = 4 days before rash, until 5 days after rash first appeared
  • Incubation period = 10-21 days

Clinical features (tend to be more severe in older children/adults)
  • Fever initially
  • Itchy rash starting from head/trunk before spreading. Initially macular then papular then vesicular
  • Systemic upset is usually mild

Management is supportive
  • Keep cool, trim nails
  • Calamine lotion
  • School exclusion: current HPA advice is 5 days from start of skin eruption
  • Immunocompromised patients and newborns with peripartum exposure should receive varicella zoster immunoglobulin (VZIG). If chickenpox develops then IV aciclovir should be considered

A common complication is secondary bacterial infection of the lesions. Rare complications include
  • Pneumonia
  • Encephalitis (cerebellar involvement may be seen)
  • Disseminated haemorrhagic chickenpox
  • Arthritis, nephritis, and pancreatitis may very rarely be seen

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