Tuesday 28 August 2012

Mesial temporal sclerosis

Neuroradiology

Mesial temporal sclerosis (hippocampal sclerosis) is a specific pattern of hippocampal neuron cell loss, and is divided into three categories based on 'sectors' affected.
  • CA1 and CA4
  • CA4 alone
  • CA1 to CA4
Characteristics
  • Hippocampal atrophy and gliosis
  • Increased T2 signal
  • May occur with other temporal lobe pathologies
  • Most common feature in temporal lobe epilepsy

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